The HIV virus first mutated and came to be around the mid 30's when a guy from Africa decided to have sexual intercourse with a female chimpanzee

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https://en.wikipedia.org/wiki/HIV

ref - https://www.reddit.com/r/todayilearned/comments/cvw7ek/til_the_hiv_virus_first_mutated_and_came_to_be/
 
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