Motor neurone disease

Motor neurone disease (MND) is a uncommon condition that affects the brain and nerves. It causes weakness that gets worse over time, more…

The Motor Neurone Disease Association funds and promotes global research into motor neurone disease (MND) and provides support to people in England, Wales and Northern Ireland

Amyotrophic Lateral Sclerosis (ALS)

In ALS, nerve cells in the brain and spinal cord that control movement stop functioning. The condition leads to paralysis, and patients eventually cannot breathe or swallow on their own. The disease afflicts about 350,000 people a year worldwide (25,000 ALS patients living in the USA), and about half of patients die within three years of diagnosis.

What Is ALS? What Are the Types and Causes?

The company expects that if the stage three trial goes well, that the US Food and Drug Administration may give regulatory approval for mass use among doctors and patients. The trial will be measured by the ALSFR-S score responder analysis and final data is expected by 2019.

BrainStorm’s first two clinical trials of its stem cell therapy treatment, called NurOwn, were conducted at Jerusalem’s Hadassah hospital and also in the United States.

During the treatment process, doctors extract cells from the bone marrow of from patients with ALS, and the cells are multiplied and matured, then prepared for injection back into the patient. During the maturation process, the cells from the bone marrow are manipulated into behaving like brain cells, in that they produce materials that are the building blocks of the brain. When these modified cells are put back in patients, the building blocks circulate in the spinal fluid and help repair the damaged brain. (src)

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By: |26/03/2018|categories: /